In a new meta-analysis recently published in JAMA, researchers investigated prevalence of withdrawal syndrome and risk factors for withdrawal syndrome among regular marijuana users. According to the DSM V, cannabis withdrawal syndrome (CWS) was defined as the presence of at least 3 of the following symptoms developing in the 7 days following reduction or cessation of marijuana use: (1) irritability, anger, or aggression; (2) nervousness or anxiety; (3) sleep disturbance; (4) appetite or weight disturbance; (5) restlessness; (6) depressed mood; and (7) somatic symptoms, such as headaches, sweating, nausea, vomiting, or abdominal pain. Occurrence of withdrawal syndrome indicates that a [...]